Affordable Innovation
HANLIKANG (rituximab injection) is the company's first proprietary product. It is the first-ever China-manufactured biosimilar approved by the NMPA in accordance with the Technical Guideline for the Development and Evaluation of Biosimilars (Tentative) issued in 2015. As of now, HANLIKANG has been approved by the NMPA for the treatment of non-Hodgkin’s lymphoma, chronic lymphocytic leukemia, and rheumatoid arthritis for which the originator rituximab has not been approved in China, benefiting a wider patient population with differentiated strategies.
HANQUYOU (trastuzumab, trade name: HERCESSI™ in the U.S., Zercepac® in Europe) was successfully launched in the U.S., China and Europe, becoming the Chinese mAb biosimilar entering the U.S., the EU and China market. It is indicated for the treatment of HER2 positive early breast cancer, metastatic breast cancer and metastatic gastric cancer, which corresponds to all the approved indications of the trastuzumab originator and brings more treatment options to patients with HER2 positive breast and gastric cancer worldwide.
HANBEITAI (bevacizumab injection) was approved by the NMPA in November 2021. It is indicated for metastatic colorectal cancer (mCRC), advanced, metastatic or recurrent non-small cell lung cancer (NSCLC), recurrent glioblastoma, cervical cancer, hepatocellular carcinoma, epithelial ovarian cancer, fallopian tube cancer or primary peritoneal cancer. Proposed to be combined with HANSIZHUANG (PD-1) for immuno-oncology combination therapies to treat various tumors.
HANNAIJIA (neratinib), an orally administered small-molecule pan-HER tyrosine kinase inhibitor (TKI), was approved by NMPA in June 2024, for the extended adjuvant treatment of adult patients with early-stage HER2-positive breast cancer, to follow adjuvant trastuzumab-based therapy. It can be used as sequential therapy after completion of HANQUYOU (trastuzumab) that is self-developed by the company to further reduce the risk of recurrence for patients with early-stage HER2-positive breast cancer.
BILDYOS® (denosumab-nxxp), independently developed and manufactured by Henlius, was approved by the U.S. Food and Drug Administration (FDA) in September 2025, marking the first “China-origin” denosumab. The product is approved for all five indications of the reference product, including osteoporosis, offering more treatment options for the growing aging population.
BILPREVDA® (denosumab-nxxp), independently developed and manufactured by Henlius, was approved by the U.S. Food and Drug Administration (FDA) in September 2025, marking the first “China-origin” denosumab. The product is approved for all three indications of the reference product, including cancer-related bone disease, offering more treatment options for the growing aging population.
